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Consistent with our results, the expression levels of these proteins were significantly higher in tumor tissues than in paracancerous tissues from patients with colon adenocarcinoma (COAD) or rectal adenocarcinoma (READ) (Human Protein Atlas) (Supplementary Fig

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However, it has been structurally modified to bind to albumin in the bloodstream, which dramatically extends its half-life to approximately six to eight days (with DAC formulation)